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    <title>Document</title>
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<body>

<audio class="skPlayer-source" controls preload="auto"><source src="https://pic.ibaotu.com/mp3Watermark_v3/00/81/14/5a16de602143c16a87ee7dc91ae429ca.mp3" type="audio/mpeg"></audio>

<button >播放</button>
<script src="https://cdnjs.cat.net/ajax/libs/jquery/2.2.4/jquery.min.js"></script>

<script>
    var audio = document.getElementsByTagName('audio')[0];
    var button = document.getElementsByTagName('button')[0];
    var source = document.getElementsByTagName('source')[0];
    $(button).bind('click',function(){
        //source.src="http://p2.music.126.net/vDBVFyat4CJcSXI_6-jzbA==/2092370627667073.mp3";//不可以播放
        var audio = document.getElementsByTagName('audio')[0];
        audio.src = "http://img02.tuke88.com/preview_music/00/00/05/seemp3-5ba0b0f6144741110.mp3";//可以播放
        console.log(audio);
        audio.paused && (audio.play())
    })
</script>

</body>
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